4717.7860 HEALTH RISK LIMITS TABLE.
§
Subpart 1.
Generally.
This table lists the health risk limits derived from methods specified in parts 4717.7830, 4717.7840, and 4717.7850. For each chemical, this table specifies:
§
C.
the year the HRL was adopted;
§
D.
the volatility classification;
§
G.
the RfD and RSC used in the derivation of any noncancer HRL;
§
H.
the slope factor and any ADAF or AFlifetime used in the derivation of any cancer HRL;
§
I.
the intake rate used in the derivation of any noncancer or cancer HRL; and
§
J.
the health endpoints.
§
Subp. 2.
Explanation of table in this part.
§
A.
"--" symbol means not relevant.
§
B.
"NA" means not applicable.
§
C.
"ND" means not derived due to absence or paucity of toxicity information.
§
D.
"None" means not applicable for inclusion in the health risk index.
§
E.
The following explanations in subitems (1) to (3) apply where noted:
§
(1)
The acute HRL value is less than the calculated HRL. To be protective of acute exposures, the HRL is set equal to the acute HRL value.
§
(2)
The short-term HRL value is less than the calculated HRL. To be protective of short-term exposures, the HRL is set equal to the short-term HRL value.
§
(3)
The subchronic HRL value is less than the calculated HRL. To be protective of subchronic exposures, the HRL is set equal to the subchronic HRL value.
§
Subp. 2a.
Acenaphthene.
|
CAS number: 83-32-9 |
|
Year Adopted: 2018 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
200 |
100 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
0.070 |
0.021 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
0.070 |
0.044 |
-- |
Endpoints
|
-- |
-- |
adrenal, hepatic (liver) system |
adrenal, hepatic (liver) system |
-- |
§
Subp. 2b.
Acetaminophen.
|
CAS number: 103-90-2 |
|
Year Adopted: 2015 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
200 |
200 |
200 (2) |
200 (2) |
NA |
RfD (mg/kg-day)
|
0.25 |
0.25 |
(2) |
(2) |
-- |
RSC
|
0.2 |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
hepatic (liver) system |
hepatic (liver) system |
hepatic (liver) system |
hepatic (liver) system |
-- |
§
Subp. 3.
Acetochlor.
|
CAS number: 34256-82-1 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
30 |
30 |
20 |
NA |
RfD (mg/kg-day)
|
-- |
0.016 |
0.012 |
0.0039 |
-- |
RSC
|
-- |
0.5 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
0.070 |
0.044 |
-- |
Endpoints
|
-- |
developmental, hepatic (liver) system, thyroid (E) |
hepatic (liver) system, male reproductive system, nervous system, renal (kidney) system |
hepatic (liver) system, male reproductive system, nervous system, renal (kidney) system, respiratory system |
-- |
§
Subp. 3a.
Acetochlor ESA.
|
CAS number: 187022-11-3 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
500 |
500 |
300 |
NA |
RfD (mg/kg-day)
|
-- |
0.29 |
0.19 |
0.056 |
-- |
RSC
|
-- |
0.5 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
0.070 |
0.044 |
-- |
Endpoints
|
-- |
thyroid (E) |
male reproductive system, thyroid (E) |
male reproductive system, thyroid (E) |
-- |
§
Subp. 3b.
Acetochlor OXA.
|
CAS number: 184992-44-4 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
100 |
100 (2) |
90 |
NA |
RfD (mg/kg-day)
|
-- |
0.081 |
(2) |
0.019 |
-- |
RSC
|
-- |
0.5 |
(2) |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
(2) |
0.044 |
-- |
Endpoints
|
-- |
thyroid (E) |
thyroid (E) |
thyroid (E) |
-- |
§
Subp. 3c.
Acetone.
|
CAS number: 67-64-1 |
|
Year Adopted: 2011 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
9,000 |
8,000 |
4,000 |
NA |
RfD (mg/kg-day)
|
-- |
5.0 |
3.0 |
0.90 |
-- |
RSC
|
-- |
0.5 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
0.077 |
0.043 |
-- |
Endpoints
|
-- |
renal (kidney) system |
renal (kidney) system, hematological (blood) system |
renal (kidney) system, hematological (blood) system |
-- |
§
Subp. 3d.
6-Acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN).
|
CAS number: 21145-77-7 or 1506-02-1 |
|
Year Adopted: 2013 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
100 |
30 |
20 |
NA |
RfD (mg/kg-day)
|
-- |
0.070 |
0.011 |
0.0037 |
-- |
RSC
|
-- |
0.5 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
0.077 |
0.043 |
-- |
Endpoints
|
-- |
hepatic (liver) system |
hepatic (liver) system |
hepatic (liver) system |
-- |
§
Subp. 3e.
Acrylamide.
|
CAS number: 79-06-1 |
|
Year Adopted: 2015 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
7 |
7 (2) |
7 (2) |
0.2 |
RfD (mg/kg-day)
|
-- |
0.010 |
(2) |
(2) |
-- |
RSC
|
-- |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.5 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) 3 (ADAF2 to <16) 1 (ADAF16+) |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
(2) |
0.137(<2) 0.047(2 to <16) 0.039(16+) |
Endpoints
|
-- |
developmental, male reproductive system, nervous system |
developmental, male reproductive system, nervous system |
developmental, male reproductive system, nervous system |
cancer |
§
Subp. 4.
Alachlor.
|
CAS number: 15972-60-8 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
100 |
60 |
9 |
NA |
RfD (mg/kg-day)
|
-- |
0.077 |
0.020 |
0.0020 |
-- |
RSC
|
-- |
0.5 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
0.070 |
0.044 |
-- |
Endpoints
|
-- |
developmental, renal (kidney) system |
hematological (blood) system, hepatic (liver) system, renal (kidney) system |
hematological (blood) system, hepatic (liver) system, renal (kidney) system |
-- |
§
Subp. 5.
Atrazine.
|
CAS number: 1912-24-9 |
|
Year Adopted: 2009 |
|
Volatility: Nonvolatile |
|
MCL-based HRL: 3 µg/L |
§
Subp. 5a.
Bentazon.
|
CAS number: 25057-89-0 |
|
Year Adopted: 2015 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
400 |
60 |
50 |
30 |
NA |
RfD (mg/kg-day)
|
0.22 |
0.033 |
0.020 |
0.0060 |
-- |
RSC
|
0.5 |
0.5 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
0.077 |
0.043 |
-- |
Endpoints
|
developmental, female reproductive system |
developmental |
hematological (blood) system |
thyroid |
-- |
§
Subp. 6.
Benzene.
|
CAS number: 71-43-2 |
|
Year Adopted: 2009 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
10 |
10 |
3 |
3 (3) |
2 |
RfD (mg/kg-day)
|
0.015 |
0.014 |
0.0013 |
(3) |
-- |
RSC
|
0.2 |
0.2 |
0.2 |
(3) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.055 |
ADAF
|
-- |
-- |
-- |
-- |
10 (ADAF<2) |
|
|
|
|
|
3 (ADAF2 to <16) |
|
|
|
|
|
1 (ADAF16+) |
Intake Rate
|
0.289 |
0.289 |
0.077 |
(3) |
0.137 (<2) |
(L/kg-day)
|
|
|
|
|
0.047 (2 to <16) |
|
|
|
|
|
0.039 (16+) |
Endpoints
|
develop- mental |
hemato- logical (blood) system, immune system |
hemato- logical (blood) system, immune system |
hemato- logical (blood) system, immune system |
cancer |
§
Subp. 6a.
[Renumbered subp 6f]
§
Subp. 6b.
[Renumbered subp 6g]
§
Subp. 6c.
Bisphenol A (BPA).
|
CAS number: 80-05-7 |
|
Year Adopted: 2015 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
100 |
20 |
20 (3) |
NA |
RfD (mg/kg-day)
|
-- |
0.16 |
0.0065 |
(3) |
-- |
RSC
|
-- |
0.2 |
0.2 |
(3) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
0.077 |
(3) |
-- |
Endpoints
|
-- |
developmental, female reproductive system (E), hepatic (liver) system, male reproductive system (E), renal (kidney) system, thyroid (E) |
hepatic (liver) system, renal (kidney) system |
hepatic (liver) system, renal (kidney) system |
-- |
§
Subp. 6d.
Butyl benzyl phthalate.
|
CAS number: 85-68-7 |
|
Year Adopted: 2015 |
|
Volatility: Low |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
100 |
100 |
100 (2) |
100 (2) |
NA |
RfD (mg/kg-day)
|
0.15 |
0.15 |
(2) |
(2) |
-- |
RSC
|
0.2 |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
developmental (E) |
developmental (E) |
developmental (E) |
developmental (E) |
-- |
§
Subp. 6e.
Cadmium.
|
CAS number: 7440-43-9 |
|
Year Adopted: 2015 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
5 |
1 |
1 |
0.5 |
NA |
RfD (mg/kg-day)
|
0.0077 |
0.0016 |
0.00044 |
0.00011 |
-- |
RSC
|
0.2 |
0.2 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
0.077 |
0.043 |
-- |
Endpoints
|
developmental |
developmental, nervous system, renal (kidney) system |
developmental, skeletal |
renal (kidney) system, skeletal |
-- |
§
Subp. 6f.
Carbamazepine.
|
CAS number: 298-46-4 |
|
Year Adopted: 2013 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
40 |
40 |
40 (2) |
40 (2) |
NA |
RfD (mg/kg-day)
|
0.013 |
0.013 |
(2) |
(2) |
-- |
RSC
|
0.8 |
0.8 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate
|
0.289 |
0.289 |
(2) |
(2) |
-- |
(L/kg-day)
|
|
|
|
|
|
Endpoints
|
develop- mental, nervous system |
develop- mental, hematological (blood) system, hepatic (liver) system, immune system, nervous system, male reproductive system (E), female reproductive system (E), thyroid (E) |
develop- mental, hematological (blood) system, hepatic (liver) system, immune system, nervous system, male reproductive system (E), female reproductive system (E), thyroid (E) |
develop- mental, hematological (blood) system, hepatic (liver) system, immune system, nervous system, male reproductive system (E), female reproductive system (E), thyroid (E) |
-- |
§
Subp. 6g.
Carbon tetrachloride.
|
CAS number: 56-23-5 |
|
Year Adopted: 2013 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
100 |
3 |
3 (2) |
3 (2) |
1 |
RfD (mg/kg-day)
|
0.18 |
0.0037 |
(2) |
(2) |
-- |
RSC
|
0.2 |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.07 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) |
|
|
|
|
|
3 (ADAF2 to <16) |
|
|
|
|
|
1 (ADAF16+) |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
(2) |
0.137 (<2) |
|
|
|
|
|
0.047 (2 to <16) |
|
|
|
|
|
0.039 (16+) |
Endpoints
|
develop- mental, hepatic (liver) system |
hepatic (liver) system |
hepatic (liver) system |
hepatic (liver) system |
cancer |
§
Subp. 7.
Chloroform.
|
CAS number: 67-66-3 |
|
Year Adopted: 2018 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
20 |
20 (2) |
20 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.022 |
(2) |
(2) |
-- |
RSC
|
-- |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
(2) |
(2) |
-- |
Endpoints
|
-- |
developmental, hepatic (liver) system, immune system |
developmental, hepatic (liver) system, immune system |
developmental, hepatic (liver) system, immune system |
-- |
§
Subp. 7a.
Clothianidin.
|
CAS number: 210880-92-5, 205510-53-8 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
200 |
200 (2) |
200 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.093 |
(2) |
(2) |
-- |
RSC
|
-- |
0.5 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
(2) |
(2) |
-- |
Endpoints
|
-- |
developmental |
developmental |
developmental |
-- |
§
Subp. 8.
Cyanazine.
|
CAS number: 21725-46-2 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
3 |
3 |
3 |
1 |
NA |
RfD (mg/kg-day)
|
0.0015 |
0.0015 |
0.0012 |
0.00022 |
-- |
RSC
|
0.5 |
0.5 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.285 |
0.285 |
0.070 |
0.044 |
-- |
Endpoints
|
developmental, female reproductive system |
developmental, female reproductive system |
developmental, female reproductive system, hepatic (liver) system, renal (kidney) system |
None |
-- |
§
Subp. 8a.
[Renumbered subp 8f]
§
Subp. 8b.
[Renumbered subp 8g]
§
Subp. 8c.
[Renumbered subp 8h]
§
Subp. 8d.
[Renumbered subp 8i]
§
Subp. 8e.
Dibutyl phthalate.
|
CAS number: 84-74-2 |
|
Year Adopted: 2015 |
|
Volatility: Low |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
20 |
20 |
20 (2) |
20 (2) |
NA |
RfD (mg/kg-day)
|
0.023 |
0.023 |
(2) |
(2) |
-- |
RSC
|
0.2 |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
developmental (E) |
developmental (E) |
developmental (E) |
developmental (E) |
-- |
§
Subp. 8f.
Dichlorodifluoromethane.
|
CAS number: 75-71-8 |
|
Year Adopted: 2011 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
ND |
700 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
-- |
0.15 |
-- |
RSC
|
-- |
-- |
-- |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
-- |
0.043 |
-- |
Endpoints
|
-- |
-- |
-- |
None |
-- |
§
Subp. 8g.
1,2-Dichloroethane.
|
CAS number: 107-06-2 |
|
Year Adopted: 2013 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
200 |
200 (2) |
60 |
1 |
RfD (mg/kg-day)
|
-- |
0.23 |
(2) |
0.012 |
-- |
RSC
|
-- |
0.2 |
(2) |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.091 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) |
|
|
|
|
|
3 (ADAF2 to <16) |
|
|
|
|
|
1 (ADAF16+) |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
0.043 |
0.137 (<2) |
|
|
|
|
|
0.047 (2 to <16) |
|
|
|
|
|
0.039 (16+) |
Endpoints
|
-- |
hepatic (liver) system |
hepatic (liver) system |
renal (kidney) system, hepatic (liver) system |
cancer |
§
Subp. 8h.
trans-1,2-Dichloroethene.
|
CAS number: 156-60-5 |
|
Year Adopted: 2013 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
200 |
40 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
0.091 |
0.0091 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
0.077 |
0.043 |
-- |
Endpoints
|
-- |
-- |
immune system |
immune system |
-- |
§
Subp. 8i.
1,1-Dichloroethylene.
|
CAS number: 75-35-4 |
|
Year Adopted: 2011 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
200 |
200 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
0.090 |
0.046 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
0.077 |
0.043 |
-- |
Endpoints
|
-- |
-- |
hepatic (liver) system |
hepatic (liver) system |
-- |
§
Subp. 9.
cis 1,2-Dichloroethylene.
|
CAS number: 156-59-2 |
|
Year Adopted: 2018 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
20 |
10 |
6 |
NA |
RfD (mg/kg-day)
|
-- |
0.033 |
0.0043 |
0.0013 |
-- |
RSC
|
-- |
0.2 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
0.070 |
0.044 |
-- |
Endpoints
|
-- |
hepatic (liver) system |
renal (kidney) system |
renal (kidney) system |
-- |
§
Subp. 10.
Dichloromethane.
|
CAS number: 75-09-2 |
|
Year Adopted: 2009 |
|
Volatility: High |
|
MCL-based HRL: 5 µg/L |
§
Subp. 10a.
2,4-Dichlorophenoxyacetic acid (2,4-D).
|
CAS number: 94-75-7 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
30 |
30 (2) |
30 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.048 |
(2) |
(2) |
-- |
RSC
|
-- |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
(2) |
(2) |
-- |
Endpoints
|
-- |
adrenal, developmental, thyroid (E) |
adrenal, developmental, thyroid (E) |
adrenal, developmental, thyroid (E) |
-- |
§
Subp. 11.
Dieldrin.
|
CAS number: 60-57-1 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
0.2 |
0.2 (2) |
0.2 |
0.006 |
RfD (mg/kg-day)
|
-- |
0.00011 |
(2) |
0.000043 |
-- |
RSC
|
-- |
0.5 |
(2) |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
16 |
AFlifetime
|
-- |
-- |
-- |
-- |
2.5 |
Intake Rate (L/kg-day)
|
-- |
0.285 |
(2) |
0.044 |
0.044 |
Endpoints
|
-- |
developmental, immune system, nervous system |
developmental, immune system, nervous system |
developmental, hepatic (liver) system, immune system, nervous system |
cancer |
§
Subp. 11a.
[Renumbered subp 11d]
§
Subp. 11b.
[Renumbered subp 11f]
§
Subp. 11c.
Di(2-ethylhexyl) phthalate (DEHP).
|
CAS number: 117-81-7 |
|
Year Adopted: 2015 |
|
Volatility: Nonvolatile |
|
|
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
20 |
20 |
20 (2) |
20 (2) |
7 |
RfD (mg/kg-day)
|
0.029 |
0.029 |
(2) |
(2) |
-- |
RSC
|
0.2 |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.014 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) 3 (ADAF2 to <16) 1 (ADAF16+) |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
(2) |
0.137(<2) 0.047(2 to <16) 0.039(16+) |
Endpoints
|
develop- mental (E), male reproductive system (E) |
develop- mental (E), male reproductive system (E) |
develop- mental (E), male reproductive system (E) |
develop- mental (E), male reproductive system (E) |
cancer |
§
Subp. 11d.
N,N-Diethyl-meta-toluamide (DEET).
|
CAS number: 134-62-3 |
|
Year Adopted: 2013 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
200 |
200 (2) |
200 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.23 |
(2) |
(2) |
-- |
RSC
|
-- |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
-- |
developmental, nervous system |
developmental, nervous system |
developmental, nervous system |
-- |
§
Subp. 11e.
Dimethenamid and Dimethenamid-p.
|
CAS numbers: 87674-68-8 and 163515-14-8 |
|
Year Adopted: 2015 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
600 |
600 (2) |
300 |
NA |
RfD (mg/kg-day)
|
-- |
0.34 |
(2) |
0.060 |
-- |
RSC
|
-- |
0.5 |
(2) |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
0.043 |
-- |
Endpoints
|
-- |
developmental, female reproductive system, hepatic (liver) system, nervous system |
developmental, female reproductive system, hepatic (liver) system, nervous system |
hepatic (liver) system |
-- |
§
Subp. 11f.
Dinoseb.
|
CAS number: 88-85-7 |
|
Year Adopted: 2018 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
8 |
8 (2) |
8 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.0048 |
(2) |
(2) |
-- |
RSC
|
-- |
0.5 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
(2) |
(2) |
-- |
Endpoints
|
-- |
developmental |
developmental |
developmental |
-- |
§
Subp. 11g.
1,4-Dioxane.
|
CAS number: 123-91-1 |
|
Year Adopted: 2013 |
|
Volatility: Low |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
300 |
100 |
1 |
RfD (mg/kg-day)
|
-- |
-- |
0.12 |
0.025 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.1 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) |
|
|
|
|
|
3 (ADAF2 to <16) |
|
|
|
|
|
1 (ADAF16+) |
Intake Rate
|
-- |
-- |
0.077 |
0.043 |
0.137 (<2) |
(L/kg-day)
|
|
|
|
|
0.047 (2 to <16) |
|
|
|
|
|
0.039 (16+) |
Endpoints
|
-- |
-- |
hepatic (liver) system, renal (kidney) system, respiratory system |
hepatic (liver) system, renal (kidney) system, respiratory system |
cancer |
§
Subp. 12.
[Repealed, 40 SR 689]
§
Subp. 12a.
Ethylbenzene.
|
CAS number: 100-41-4 |
|
Year Adopted: 2011 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
50 |
50 (2) |
50 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.075 |
(2) |
(2) |
-- |
RSC
|
-- |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
-- |
hepatic (liver) system, renal (kidney) system |
hepatic (liver) system, renal (kidney) system |
hepatic (liver) system, renal (kidney) system |
-- |
§
Subp. 12b.
S-Ethyl-N,N-dipropylthiocarbamate (EPTC).
|
CAS number: 759-94-4 |
|
Year Adopted: 2018 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
300 |
300 |
90 |
40 |
NA |
RfD (mg/kg-day)
|
0.16 |
0.16 |
0.033 |
0.0083 |
-- |
RSC
|
0.5 |
0.5 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.285 |
0.285 |
0.070 |
0.044 |
-- |
Endpoints
|
nervous system |
developmental, female reproductive system, nervous system |
cardiovascular system |
cardiovascular system |
-- |
§
Subp. 12c.
Ethylene glycol.
|
CAS number: 107-21-1 |
|
Year Adopted: 2011 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
4,000 |
4,000 |
2,000 |
2,000 |
NA |
RfD (mg/kg-day)
|
0.76 |
0.76 |
0.72 |
0.50 |
-- |
RSC
|
0.2 |
0.2 |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.043 |
0.043 |
0.077 |
0.043 |
-- |
Endpoints
|
developmental |
developmental |
renal (kidney) system, developmental |
renal (kidney) system, developmental |
-- |
§
Subp. 12d.
Fluoranthene.
|
CAS number: 206-44-0 |
|
Year Adopted: 2018 |
|
Volatility: Low |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
200 |
70 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
0.053 |
0.016 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
0.070 |
0.044 |
-- |
Endpoints
|
-- |
-- |
hepatic (liver) system, renal (kidney) system |
hepatic (liver) system, renal (kidney) system |
-- |
§
Subp. 12e.
Metolachlor and S-Metolachlor.
|
CAS number: 51218-45-2; 87392-12-9 |
|
Year Adopted: 2011 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
400 |
400 |
300 |
300 (3) |
NA |
RfD (mg/kg-day)
|
0.24 |
0.24 |
0.097 |
(3) |
-- |
RSC
|
0.5 |
0.5 |
0.2 |
(3) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
0.077 |
(3) |
-- |
Endpoints
|
developmental |
developmental |
none |
none |
-- |
§
Subp. 12f.
Metolachlor ESA.
|
CAS number: 171118-09-5 |
|
Year Adopted: 2011 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
4,000 |
800 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
1.7 |
0.17 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
0.077 |
0.043 |
-- |
Endpoints
|
-- |
-- |
hepatic (liver) system |
hepatic (liver) system |
-- |
§
Subp. 12g.
Metolachlor OXA.
|
CAS number: 152019-73-3 |
|
Year Adopted: 2011 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
3,000 |
3,000 (2) |
800 |
NA |
RfD (mg/kg-day)
|
-- |
1.7 |
(2) |
0.17 |
-- |
RSC
|
-- |
0.5 |
(2) |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
0.043 |
-- |
Endpoints
|
-- |
none |
none |
none |
-- |
§
Subp. 12h.
Metribuzin.
|
CAS number: 21087-64-9 |
|
Year Adopted: 2013 |
|
Volatility: Low |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
30 |
10 |
10 (2) |
10 (2) |
NA |
RfD (mg/kg-day)
|
0.016 |
0.006 |
(2) |
(2) |
-- |
RSC
|
0.5 |
0.5 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
developmental, nervous system |
thyroid (E) |
thyroid (E) |
thyroid (E) |
-- |
§
Subp. 12i.
Naphthalene.
|
CAS number: 91-20-3 |
|
Year Adopted: 2013 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
70 |
70 |
70 (2) |
70 |
NA |
RfD (mg/kg-day)
|
0.038 |
0.038 |
(2) |
0.016 |
-- |
RSC
|
0.5 |
0.5 |
(2) |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
0.043 |
-- |
Endpoints
|
nervous system |
nervous system |
nervous system |
nervous system, spleen |
-- |
§
Subp. 13.
Nitrate (as N).
|
CAS number: 14797-55-8 |
|
Year Adopted: 2009 |
|
Volatility: Nonvolatile |
|
MCL-based HRL: 10,000 µg/L |
§
Subp. 14.
Pentachlorophenol (PCP).
|
CAS number: 87-86-5 |
|
Year Adopted: 2015 |
|
Volatility: Low |
|
|
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
7 |
7 |
7 (2) |
7 (2) |
0.3 |
RfD (mg/kg-day)
|
0.0040 |
0.0040 |
(2) |
(2) |
-- |
RSC
|
0.5 |
0.5 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.4 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) 3 (ADAF2 to <16) 1 (ADAF16+) |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
(2) |
0.137(<2) 0.047(2 to <16) 0.039(16+) |
Endpoints
|
develop- mental, thyroid (E) |
develop- mental (E), thyroid (E) |
develop- mental (E), hepatic (liver) system, immune system, male reproductive system, thyroid (E) |
develop- mental (E), hepatic (liver) system, immune system, male reproductive system, thyroid (E) |
cancer |
§
Subp. 14a.
Perfluorobutane sulfonate (PFBS).
|
CAS number: 375-73-5 |
|
Year Adopted: 2011 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
9 |
7 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
0.0042 |
0.0014 |
-- |
RSC
|
-- |
-- |
0.5 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
0.245 |
0.043 |
-- |
Endpoints
|
-- |
-- |
hepatic (liver) system, hematological (blood) system, renal (kidney) system |
hepatic (liver) system, hematological (blood) system, renal (kidney) system |
-- |
§
Subp. 14b.
Perfluorobutanoate (PFBA).
|
CAS number: 45048-62-2; 375-22-4 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
7 |
7 (2) |
7 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.0038 |
(2) |
(2) |
-- |
RSC
|
-- |
0.5 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
(2) |
(2) |
-- |
Endpoints
|
-- |
hepatic (liver) system, thyroid (E) |
hepatic (liver) system, thyroid (E) |
hepatic (liver) system, thyroid (E) |
-- |
§
Subp. 15.
Perfluorooctane sulfonate (PFOS) and salts.
|
CAS number: 45298-90-6; 1763-23-1; 29081-56-9; 2795-39-3; 70225-14-8; and 29457-72-5 |
|
Year Adopted: 2009 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
ND |
0.3 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
-- |
0.00008 |
-- |
RSC
|
-- |
-- |
-- |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
-- |
0.049 |
-- |
Endpoints
|
-- |
-- |
-- |
developmental, hepatic (liver) system, thyroid (E) |
-- |
§
Subp. 16.
Perfluorooctanoate (PFOA) and salts.
|
CAS number: 45285-51-6; 335-67-1; 335-66-0; 3825-26-1; 2395-00-8; 335-93-3; and 335-95-5 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
0.035 |
0.035 |
0.035 |
NA |
RfD (mg/kg-day)
|
-- |
0.000018 |
0.000018 |
0.000018 |
-- |
RSC
|
-- |
0.5 |
0.5 |
0.5 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
* |
* |
* |
-- |
Endpoints
|
-- |
developmental, hepatic (liver) system, immune system, renal (kidney) system |
developmental, hepatic (liver) system, immune system, renal (kidney) system |
developmental, hepatic (liver) system, immune system, renal (kidney) system |
-- |
* 95th percentile water intake rates (Tables 3-1 and 3-3), or upper percentile breast milk intake rates (Table 15-1), Environmental Protection Agency (EPA) Exposure Factors Handbook, 2011.
§
Subp. 16a.
Pyrene.
|
CAS number: 129-00-0 |
|
Year Adopted: 2018 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
90 |
50 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
0.033 |
0.010 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
0.070 |
0.044 |
-- |
Endpoints
|
-- |
-- |
renal (kidney) system |
renal (kidney) system |
-- |
§
Subp. 17.
Simazine.
|
CAS number: 122-34-9 |
|
Year Adopted: 2009 |
|
Volatility: Nonvolatile |
|
MCL-based HRL: 4 µg/L |
§
Subp. 17a.
Sulfamethazine (includes sodium salt form).
|
CAS number: 57-68-1 (1981-58-4) |
|
Year Adopted: 2015 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
100 |
100 (2) |
100 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.040 |
(2) |
(2) |
-- |
RSC
|
-- |
0.8 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
-- |
thyroid |
thyroid |
thyroid |
-- |
§
Subp. 18.
1,1,2,2-Tetrachloroethylene.
|
CAS number: 127-18-4 |
|
Year Adopted: 2009 |
|
Volatility: High |
|
MCL-based HRL: 5 µg/L |
§
Subp. 18a.
Tetrahydrofuran.
|
CAS number: 109-99-9 |
|
Year Adopted: 2018 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
600 |
600 (2) |
600 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.82 |
(2) |
(2) |
-- |
RSC
|
-- |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
(2) |
(2) |
-- |
Endpoints
|
-- |
developmental |
developmental |
developmental |
-- |
§
Subp. 18b.
Thiamethoxam.
|
CAS number: 153719-23-4 |
|
Year Adopted: 2018 |
|
Volatility: Nonvolatile |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
400 |
200 |
200 (3) |
NA |
RfD (mg/kg-day)
|
-- |
0.25 |
0.057 |
(3) |
-- |
RSC
|
-- |
0.5 |
0.2 |
(3) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.285 |
0.070 |
(3) |
-- |
Endpoints
|
-- |
developmental, female reproductive system, hepatic (liver) system |
male reproductive system |
male reproductive system |
-- |
§
Subp. 18c.
Toluene.
|
CAS number: 108-88-3 |
|
Year Adopted: 2011 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
200 |
200 (2) |
200 (2) |
NA |
RfD (mg/kg-day)
|
-- |
0.22 |
(2) |
(2) |
-- |
RSC
|
-- |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
-- |
immune system, nervous system |
immune system, nervous system |
immune system, nervous system |
-- |
§
Subp. 18d.
1,2,4-Trichlorobenezene.
|
CAS number: 120-82-1 |
|
Year Adopted: 2013 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
100 |
100 (2) |
100 |
4 |
RfD (mg/kg-day)
|
-- |
0.17 |
(2) |
0.021 |
-- |
RSC
|
-- |
0.2 |
(2) |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.029 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) |
|
|
|
|
|
3 (ADAF2 to <16) |
|
|
|
|
|
1 (ADAF16+) |
Intake Rate
|
-- |
0.289 |
(2) |
0.043 |
0.137 (<2) |
(L/kg-day)
|
|
|
|
|
0.047 (2 to <16) |
|
|
|
|
|
0.039 (16+) |
Endpoints
|
-- |
hepatic (liver) system, adrenal (E), hemato- logical (blood) system |
hepatic (liver) system, adrenal (E), hemato- logical (blood) system |
hepatic (liver) system, adrenal (E), renal (kidney) system |
cancer |
§
Subp. 19.
1,1,1-Trichloroethane.
|
CAS number: 71-55-6 |
|
Year Adopted: 2018 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
9,000 |
5,000 |
NA |
RfD (mg/kg-day)
|
-- |
-- |
3.0 |
1.0 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
-- |
0.070 |
0.044 |
-- |
Endpoints
|
-- |
-- |
hepatic (liver) system, male reproductive system |
hepatic (liver) system, male reproductive system |
-- |
§
Subp. 20.
1,1,2-Trichloroethylene (TCE).
|
CAS number: 79-01-6 |
|
Year Adopted: 2015 |
|
Volatility: High |
|
|
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
0.4 |
0.4 |
0.4 (3) |
2 |
RfD (mg/kg-day)
|
-- |
0.00052 |
0.00017 |
(3) |
-- |
RSC
|
-- |
0.2 |
0.2 |
(3) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.05 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) 3 (ADAF2 to <16) 1 (ADAF16+) |
Intake Rate (L/kg-day)
|
-- |
0.289 |
0.077 |
(3) |
0.137(<2) 0.047(2 to <16) 0.039(16+) |
Endpoints
|
-- |
develop- mental, immune system |
develop- mental, immune system |
develop- mental, immune system |
cancer |
§
Subp. 21.
2(2,4,5-Trichlorophenoxy)propionic acid (2,4,5-TP or Silvex).
|
CAS number: 93-72-1 |
|
Year Adopted: 2009 |
|
Volatility: Nonvolatile |
|
MCL-based HRL: 50 µg/L |
§
Subp. 21a.
1,2,3-Trichloropropane.
|
CAS number: 96-18-4 |
|
Year Adopted: 2013 |
|
Volatility: Moderate |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
7 |
7 |
7 (2) |
7 (2) |
0.003 |
RfD (mg/kg-day)
|
0.0042 |
0.0042 |
(2) |
(2) |
-- |
RSC
|
0.5 |
0.5 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
30 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) |
|
|
|
|
|
3 (ADAF2 to <16) |
|
|
|
|
|
1 (ADAF16+) |
Intake Rate
|
0.289 |
0.289 |
(2) |
(2) |
0.137 (<2) |
(L/kg-day)
|
|
|
|
|
0.047 (2 to <16) |
|
|
|
|
|
0.039 (16+) |
Endpoints
|
develop- mental |
develop- mental |
develop- mental |
develop- mental |
cancer |
§
Subp. 22.
1,3,5-Trimethylbenzene.
|
CAS number: 108-67-8 |
|
Year Adopted: 2009 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
100 |
100 (2) |
100 (2) |
NA |
RfD (mg/kg-day)
|
ND |
0.14 |
(2) |
(2) |
-- |
RSC
|
-- |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
-- |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
-- |
hepatic (liver) system |
hepatic (liver) system, renal (kidney) system |
hepatic (liver) system, renal (kidney) system |
-- |
§
Subp. 22a.
Tris(2-chloroethyl) phosphate.
|
CAS number: 115-96-8 |
|
Year Adopted: 2013 |
|
Volatility: Low |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
300 |
200 |
200 (3) |
5 |
RfD (mg/kg-day)
|
-- |
0.15 |
0.068 |
(3) |
-- |
RSC
|
-- |
0.5 |
0.2 |
(3) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
0.02 |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
10 (ADAF<2) |
|
|
|
|
|
3 (ADAF2 to <16) |
|
|
|
|
|
1 (ADAF16+) |
Intake Rate
|
-- |
0.289 |
0.077 |
(3) |
0.137 (<2) |
(L/kg-day)
|
|
|
|
|
0.047 (2 to <16) |
|
|
|
|
|
0.039 (16+) |
Endpoints
|
-- |
renal (kidney) system, nervous system, develop- mental |
renal (kidney) system |
renal (kidney) system |
cancer |
§
Subp. 23.
Vinyl Chloride.
|
CAS number: 75-01-4 |
|
Year Adopted: 2018 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
ND |
ND |
90 |
10 |
0.2 |
RfD (mg/kg-day)
|
-- |
-- |
0.033 |
0.0030 |
-- |
RSC
|
-- |
-- |
0.2 |
0.2 |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
1.4 |
AFlifetime
|
-- |
-- |
-- |
-- |
1 |
Intake Rate (L/kg-day)
|
-- |
-- |
0.070 |
0.044 |
0.044 |
Endpoints
|
-- |
-- |
hepatic (liver) system |
hepatic (liver) system |
cancer |
§
Subp. 23a.
Xylenes.
|
CAS number: 1330-20-7 |
|
Year Adopted: 2011 |
|
Volatility: High |
|
Acute
|
Short-term
|
Subchronic
|
Chronic
|
Cancer
|
HRL (µg/L)
|
800 |
300 |
300 (2) |
300 (2) |
NA |
RfD (mg/kg-day)
|
1.2 |
0.5 |
(2) |
(2) |
-- |
RSC
|
0.2 |
0.2 |
(2) |
(2) |
-- |
SF (per mg/kg-day)
|
-- |
-- |
-- |
-- |
-- |
ADAF or AFlifetime
|
-- |
-- |
-- |
-- |
-- |
Intake Rate (L/kg-day)
|
0.289 |
0.289 |
(2) |
(2) |
-- |
Endpoints
|
nervous system |
nervous system |
renal (kidney) system, nervous system |
renal (kidney) system, nervous system |
-- |
§
Subp. 24.
Transition.
The health risk limits established for the specific chemicals in this part supersede the health risk limits for those chemicals in part 4717.7500. For chemicals not included in this part, the health risk limits established in part 4717.7500 remain in place.
History:
33 SR 1792; 35 SR 1395; 38 SR 397; 40 SR 689; 43 SR 262